SCHEMBL2372586

SCHEMBL2372586

O=Cc1ccc(O)cc1OO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.44
TRIM24 O15164 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
ALDH1A1 P00352 2/20 0.41
ERN1 O75460 4/20 0.41
APP P05067 1/20 0.41
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH5A1 P51649 1/20 0.38
ABAT P80404 1/20 0.38
TTR P02766 2/20 0.38
MAOB P27338 1/20 0.38
SYNJ2 O15056 1/20 0.37
CYP1A1 P04798 1/20 0.37
BCHE P06276 1/20 0.37
MMP2 P08253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37462 0.82 ALDH1A1 (0.63) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL24794132 0.82 TYR (0.43) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL28582910 0.79 CYP3A4 (0.46) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL295293 0.77 ALDH1A1 (0.51) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL2352458 0.77 ERN1 (0.44) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL15534680 0.77 APP (0.42) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL19524136 0.77 LMNA (0.46) TYRTRIM24TRIM33ALDH1A1CTSL
SCHEMBL5308227 0.76 ALDH1A1 (0.47) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL7913737 0.75 TRIM24 (0.47) TYRTRIM24TRIM33ALDH1A1ERN1
SCHEMBL29952866 0.75 TRIM24 (0.47) TYRTRIM24TRIM33ALDH1A1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111635385-B Mitochondrion-targeted two-photon excitation near-infrared emission hydrogen sulfide fluorescent probe and preparation method and application thereof 中南林业科技大学 2023-03-24 CN claimed
CN-111635385-A Mitochondrion-targeted two-photon excitation near-infrared emission hydrogen sulfide fluorescent probe and preparation method and application thereof 中南林业科技大学 2020-09-08 CN claimed
CN-111635385-B Mitochondrion-targeted two-photon excitation near-infrared emission hydrogen sulfide fluorescent probe and preparation method and application thereof 中南林业科技大学 2023-03-24 CN disclosed
CN-111635385-A Mitochondrion-targeted two-photon excitation near-infrared emission hydrogen sulfide fluorescent probe and preparation method and application thereof 中南林业科技大学 2020-09-08 CN disclosed
US-20130008331-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2013-01-10 US disclosed
EP-2366545-B1 A lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-12-05 EP disclosed
WO-2011113693-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-09-22 WO disclosed
EP-2366545-A1 A lithographic printing plate precursor Agfa Graphics N.V. (BE) 2011-09-21 EP disclosed