Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520815 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL623439 | 0.77 | TDP1 (0.36) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL29438802 | 0.77 | TDP1 (0.36) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL29906624 | 0.77 | TRIM24 (0.48) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL3102823 | 0.77 | TRIM24 (0.48) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL4597958 | 0.76 | ALDH1A1 (0.38) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL3509732 | 0.74 | TDP1 (0.39) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL15873266 | 0.74 | TRIM24 (0.36) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL23725196 | 0.74 | ERN1 (0.41) | TRIM24TRIM33TDP1MEN1LMNA | |
| SCHEMBL15940534 | 0.74 | ALDH1A1 (0.44) | TRIM24TRIM33TDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062427-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-03-05 | — | — | US | disclosed |
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
| WO-2025096706-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2024188288-A2 | SMALL MOLECULE MODULATORS OF IL-17A, METHODS OF MAKING AND METHODS OF USING THEREOF | Ascletis BioScience Co., Ltd (CN) | 2024-09-19 | — | — | WO | disclosed |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-11708351-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708351-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4100381-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2022-12-14 | — | — | EP | disclosed |
| CN-115413275-A | Substituted 1,1 , -biphenyl compounds and methods of use thereof | 爱彼特生物制药公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-114195789-B | Preparation method of polycyclic indole derivative without participation of metal | 广东海洋大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-114195789-A | Preparation method of polycyclic indole derivative without metal participation | 广东海洋大学 | 2022-03-18 | — | — | CN | disclosed |
| WO-2021158481-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| US-20170166543-A1 | COMPOSITIONS AND METHODS FOR SYNTHESIZING (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYL-AMIDO-3-METHYLBUTANE ETHYL ESTER | AMERICAN LIFE SCIENCE PHARMACEUTICALS INC (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708351-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | CFD, TFPI, CFH | TRIM24 4226/4885TRIM33 4021/4885TDP1 4535/4885 |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, TFPI, CFH | TRIM24 4226/4885TRIM33 4021/4885TDP1 4535/4885 |
| US-20170166543-A1 | COMPOSITIONS AND METHODS FOR SYNTHESIZING (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYL-AMIDO-3-METHYLBUTANE ETHYL ESTER | PTMS, LTA, LPXN | TRIM24 2735/4885TRIM33 1567/4885TDP1 2375/4885 |
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | NR0B1, NR2C2, ERBB2 | TRIM24 2477/4885TRIM33 4023/4885TDP1 3704/4885 |
| US-20260062427-A1 | Bicyclic Ureas As Kinase Inhibitors | OXSR1, NCOR1, NR0B1 | TRIM24 2270/4885TRIM33 3934/4885TDP1 3082/4885 |
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | HAVCR2, HMBS, VHL | TRIM24 2052/4885TRIM33 1456/4885TDP1 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.