Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092189 | 1.00 | TSHR (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL222657 | 0.96 | — | — | |
| Bicarbonate SCHEMBL28339996 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Bicarbonate SCHEMBL347346 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Bicarbonate SCHEMBL270124 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12092182 | 0.84 | TSHR (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12092216 | 0.84 | TSHR (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Bicarbonate SCHEMBL10762215 | 0.84 | POLB (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Bicarbonate SCHEMBL932354 | 0.84 | POLB (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Succinic Acid SCHEMBL28486194 | 0.83 | ABCC4 (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100404-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |