Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19891056 | 0.86 | HTR1A (0.40) | DRD2SLC6A4ADRA1AHTR1AHTR2A | |
| SCHEMBL12437737 | 0.81 | DRD2 (0.64) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL19088099 | 0.78 | HTR1A (0.61) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL20389575 | 0.77 | DRD2 (0.66) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL21066151 | 0.69 | DRD3 (0.42) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL20390125 | 0.68 | DRD2 (0.47) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL30839769 | 0.67 | DRD2 (0.66) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL25003005 | 0.67 | DRD2 (0.66) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL21775922 | 0.67 | DRD3 (0.41) | DRD2SLC6A2SLC6A4DRD3ADRA1A | |
| SCHEMBL20404033 | 0.66 | GAA (0.49) | DRD2DRD3MEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397636-B1 | PROCESS FOR THE PREPARATION OF QUINOLINE-2(1H)-ONE DERIVATIVES | HONOUR R&D (IN) | 2021-08-04 | — | — | EP | disclosed |