Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24940811 | 0.86 | HSD11B1 (0.39) | HSD11B1ALDH1A1RAB9A | |
| SCHEMBL26700706 | 0.84 | HRH3 (0.43) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL23593923 | 0.82 | SMN1; SMN2 (0.37) | ALDH1A1KMT2APOLBKDM4EMEN1 | |
| SCHEMBL26221592 | 0.82 | NPC1 (0.39) | HSD11B1ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL12605278 | 0.79 | DRD3 (0.49) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL25819453 | 0.77 | POLB (0.43) | HSD11B1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL26746316 | 0.77 | GAA (0.42) | HSD11B1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL25029557 | 0.76 | NPC1 (0.40) | ALDH1A1KMT2APOLBMEN1RAB9A | |
| SCHEMBL12141777 | 0.76 | HSD11B1 (0.53) | HSD11B1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL27051250 | 0.76 | FAAH (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |