Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26700717 | 0.84 | HRH3 (0.48) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL23729436 | 0.84 | HSD11B1 (0.44) | HRH3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16132779 | 0.83 | HRH3 (0.44) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL19661326 | 0.82 | CASP6 (0.36) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL26706354 | 0.82 | HRH3 (0.46) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL26706352 | 0.82 | HRH3 (0.46) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL23594438 | 0.82 | L3MBTL1 (0.44) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL23729438 | 0.81 | HRH3 (0.40) | HRH3KDM4EALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL24891109 | 0.81 | HRH3 (0.42) | HRH3KDM4EALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL26221592 | 0.81 | NPC1 (0.39) | ALDH1A1L3MBTL1MEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, BRCA1 | HRH3 3051/4885KDM4E 2184/4885ALDH1A1 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.