Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798971 | 0.82 | MAOA (0.33) | MAOAMAOBALDH1A1CYP1A2NLRP3 | |
| SCHEMBL24457968 | 0.74 | EED (0.33) | MAOAMAOB | |
| SCHEMBL22306947 | 0.74 | EED (0.30) | — | |
| SCHEMBL3604621 | 0.73 | ALDH1A1 (0.33) | MAOAMAOBALDH1A1CYP1A2NLRP3 | |
| SCHEMBL3600451 | 0.73 | MAOA (0.31) | MAOAMAOBALDH1A1CYP1A2NLRP3 | |
| SCHEMBL23729378 | 0.71 | ALDH1A1 (0.34) | MAOBALDH1A1 | |
| SCHEMBL3600857 | 0.69 | UGT2B17 (0.36) | MAOAMAOBALDH1A1 | |
| SCHEMBL27376978 | 0.69 | HTR2A (0.33) | MAOAMAOBALDH1A1CYP1A2 | |
| SCHEMBL22306380 | 0.68 | PARP1 (0.33) | MAOAMAOB | |
| SCHEMBL26700035 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |