Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604621 | 0.82 | ALDH1A1 (0.33) | MAOAMAOBALDH1A1CYP1A2NLRP3 | |
| SCHEMBL23729554 | 0.82 | MAOA (0.31) | MAOAMAOBALDH1A1CYP1A2NLRP3 | |
| SCHEMBL3600451 | 0.82 | MAOA (0.31) | MAOAMAOBALDH1A1CYP1A2NLRP3 | |
| SCHEMBL22306947 | 0.79 | EED (0.30) | — | |
| SCHEMBL18029587 | 0.76 | NLRP3 (0.33) | ALDH1A1NLRP3LMNATP53GAA | |
| SCHEMBL28121913 | 0.75 | HPGD (0.39) | MAOBHPGDHSD17B10 | |
| SCHEMBL3600857 | 0.74 | UGT2B17 (0.36) | MAOAMAOBALDH1A1TSHRKDM4E | |
| SCHEMBL11996624 | 0.74 | MAOA (0.41) | MAOAMAOBALDH1A1CYP1A2DRD1 | |
| SCHEMBL3601100 | 0.74 | RAB9A (0.35) | MAOAMAOBALDH1A1CYP1A2TP53 | |
| SCHEMBL18029588 | 0.74 | PARP1 (0.34) | ALDH1A1CYP1A2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-0125059-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-02-27 | — | — | EP | disclosed |
| EP-0095330-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1987-11-19 | — | — | EP | disclosed |
| US-4664693-A | POSTEMERGENCE | ICI AUSTRALIA LIMITED (AU) | 1987-05-12 | — | — | US | disclosed |
| US-4511391-A | Cyclohexane-1,3-dione derivatives and their herbicidal compositions and methods | ICI AUSTRALIA LIMITED (AU) | 1985-04-16 | — | — | US | disclosed |
| EP-0125059-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |
| EP-0095330-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-11-30 | — | — | EP | disclosed |