Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730160 | 1.00 | KDM4C (0.39) | KDM4CPHF8KDM4AKDM2AEPHX2 | |
| SCHEMBL23730156 | 0.95 | LMNA (0.38) | KDM4CPHF8KDM4AKDM2AEPHX2 | |
| SCHEMBL26479835 | 0.86 | KDM4C (0.44) | KDM4CPHF8KDM4AKDM2AEPHX2 | |
| SCHEMBL21227661 | 0.85 | EPHX2 (0.47) | EPHX2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL22872799 | 0.85 | EPHX2 (0.47) | EPHX2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL23872567 | 0.83 | KDM4C (0.54) | KDM4CPHF8KDM4AKDM2AEPHX2 | |
| SCHEMBL21227763 | 0.83 | KDM4C (0.54) | KDM4CPHF8KDM4AKDM2AEPHX2 | |
| Hydrochloric Acid SCHEMBL10671346 | 0.81 | ALDH1A1 (0.47) | KDM4CPHF8EPHX2ALDH1A1KMT2A | |
| SCHEMBL23730168 | 0.81 | LMNA (0.41) | KDM4CPHF8KDM4AKDM2AEPHX2 | |
| SCHEMBL22872800 | 0.81 | KDM4C (0.51) | KDM4CPHF8KDM4AKDM2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |