Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 5/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782469 | 0.89 | LMNA (0.50) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL28177818 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL17914173 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL2058987 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL2058434 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL2058928 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL2058893 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL2058827 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2KMT2ATDP1 | |
| SCHEMBL23730160 | 0.81 | KDM4C (0.39) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL23729624 | 0.81 | KDM4C (0.39) | LMNAALDH1A1BCHEACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |