Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729676 | 0.83 | HTR3A (0.35) | HTR3AADORA3ADORA2BADORA1ALDH1A1 | |
| SCHEMBL23729701 | 0.80 | HPD (0.39) | ADORA2BSMN1; SMN2ADORA2ATP53 | |
| SCHEMBL23730135 | 0.79 | HPD (0.40) | ADORA2BALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23730109 | 0.78 | HPD (0.34) | ADORA2BADORA2A | |
| SCHEMBL23729681 | 0.77 | HPD (0.36) | ADORA2BADORA2A | |
| SCHEMBL23730108 | 0.76 | HPD (0.36) | ADORA2BALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23729332 | 0.75 | CNR2 (0.35) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL23729337 | 0.75 | HPD (0.33) | ADORA2BADORA2A | |
| SCHEMBL23729679 | 0.75 | HPD (0.33) | ADORA2BADORA1ALDH1A1GAAKDM4E | |
| SCHEMBL23730201 | 0.71 | ADORA2B (0.44) | HTR3AADORA3ADORA2BADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858818-A1 | TRIKETONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND HERBICIDE | Shandong Cynda Chemical Co., LTD. (CN) | 2021-08-04 | — | — | EP | disclosed |