SCHEMBL23729962

SCHEMBL23729962

COC(=O)c1ccc(F)cc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.52
FFAR4 Q5NUL3 1/20 0.48
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
NPC1 O15118 1/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
PDK2 Q15119 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
PDK4 Q16654 1/20 0.46
PLA2G2A P14555 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708451 0.90 SLC6A4 (0.51) FFAR4SLC6A4SLC6A3NPC1CASP3
SCHEMBL30301996 0.90 SLC6A4 (0.51) FFAR4SLC6A4SLC6A3NPC1CASP3
SCHEMBL16954819 0.85 SLC6A4 (0.47) FFAR4SLC6A4SLC6A3NPC1CASP3
SCHEMBL1957013 0.84 SLC6A4 (0.46) KEAP1FFAR4SLC6A4SLC6A3NPC1
SCHEMBL15273593 0.82 SLC6A4 (0.45) FFAR4SLC6A4SLC6A3NPC1CASP3
SCHEMBL336978 0.82 KEAP1 (0.65) KEAP1SLC6A4CA12CA1CA2
SCHEMBL30520290 0.82 KEAP1 (0.65) KEAP1SLC6A4CA12CA1CA2
SCHEMBL1790176 0.82 SLC6A3 (0.50) SLC6A4SLC6A3NPC1RAB9ASMN1; SMN2
SCHEMBL112046 0.81 CES2 (0.61) FFAR4SLC6A4SLC6A3NPC1CASP3
SCHEMBL14012584 0.81 CES2 (0.61) FFAR4SLC6A4SLC6A3NPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436910-B Diazonaphthoquinone sulfonate compound and resin composition 北京鼎材科技有限公司 2024-01-26 CN disclosed
CN-114436910-A Diazonaphthoquinone sulfonate compound and resin composition 北京鼎材科技有限公司 2022-05-06 CN disclosed
WO-2021155321-A2 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2021-08-05 WO disclosed
CN-104955456-A N-substituted-5-substituted anthranilic acids as sortilin inhibitors LUNDBECK & CO AS H 2015-09-30 CN disclosed