SCHEMBL2373038

SCHEMBL2373038

Cn1cc2c(n1)CNC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2750120 0.98 SOD3 (0.34)
SCHEMBL6421992 0.82 HTR2C (0.45)
SCHEMBL16217168 0.82 HTR2C (0.45)
Hydrochloric Acid SCHEMBL31119454 0.80 HTR2C (0.44)
SCHEMBL18806203 0.75 AADAT (0.36)
SCHEMBL21990816 0.74
SCHEMBL18806097 0.74 PDK2 (0.38)
SCHEMBL31652215 0.74 HTR2C (0.34)
SCHEMBL34469209 0.71 PNMT (0.40)
SCHEMBL15203113 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552918-B1 N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS HOFFMANN LA ROCHE (CH) 2014-06-11 EP claimed
US-8410117-B2 Imidazopyrimidine derivatives HOFFMANN-LA ROCHE INC. (US) 2013-04-02 US claimed
EP-2552918-A1 N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS F. Hoffmann-La Roche AG (CH) 2013-02-06 EP claimed
US-20110237564-A1 IMIDAZOPYRIMIDINE DERIVATIVES HOFFMANN-LA ROCHE INC. 2011-09-29 US claimed
WO-2011117264-A1 N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2011-09-29 WO claimed
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP disclosed
CN-119998275-A KRAS inhibitors 百时美施贵宝公司 2025-05-13 CN disclosed
EP-4486453-A1 BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS F. Hoffmann-La Roche AG (CH) 2025-01-08 EP disclosed
WO-2024183793-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF 上海海和药物研究开发股份有限公司 2024-09-12 WO disclosed
US-20240199584-A1 KRAS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2024-06-20 US disclosed
CN-117242073-A PRMT5 inhibitors and uses thereof 海思科医药集团股份有限公司 2023-12-15 CN disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 US disclosed
US-20110237564-A1 IMIDAZOPYRIMIDINE DERIVATIVES HOFFMANN-LA ROCHE INC. 2011-09-29 US disclosed
WO-2011117264-A1 N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2011-09-29 WO disclosed
US-20100204477-A1 Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones MICURX PHARMACEUTICALS, INC. (KY) 2010-08-12 US disclosed
US-20100204477-A1 Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones MICURX PHARMACEUTICALS, INC. (KY) 2010-08-12 US disclosed
WO-2010091272-A1 METHODS AND PROCESSES FOR SYNTHESES AND MANUFACTURE OF ANTIMICROBIAL 1-(ORTHO-FLUOROPHENYL)DIHYDROPYRIDONES MICURX PHARMACEUTICALS, INC. (US) 2010-08-12 WO disclosed
US-20090048305-A1 Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) 2009-02-19 US disclosed
US-20090048305-A1 Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) 2009-02-19 US disclosed
WO-2009020616-A1 ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS MICURX PHARMACEUTICALS, INC. (KY) 2009-02-12 WO disclosed