Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607036 | 0.88 | KMT2A (0.51) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL8775304 | 0.87 | KMT2A (0.57) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL3494511 | 0.86 | KMT2A (0.55) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL973673 | 0.86 | KMT2A (0.69) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL4666968 | 0.86 | MEN1 (0.55) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL436607 | 0.84 | TRPA1 (0.48) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL5450997 | 0.83 | MEN1 (0.56) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL11785273 | 0.83 | ADRB2 (0.40) | KMT2AMEN1NPC1MDM2ALDH1A1 | |
| SCHEMBL3589983 | 0.82 | KMT2A (0.51) | KMT2AMEN1NPC1TDP1MMP8 | |
| SCHEMBL12003491 | 0.81 | MEN1 (0.53) | KMT2AMEN1NPC1TDP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | MGAM, CMBL, MGAM2 | KMT2A 1387/4885MEN1 2730/4885NPC1 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.