SCHEMBL23732240

SCHEMBL23732240

Cc1cc(C)c(O)c(C(=O)NCCC(=O)O)n1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 12/20 0.50
KDM4E B2RXH2 1/20 0.49
KMT2A Q03164 1/20 0.49
EGLN1 Q9GZT9 15/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL1251838 0.73 KDM4E (0.46) KDM4EKMT2AEGLN1
SCHEMBL19071999 0.69 ITGB3 (0.52) KDM4EKMT2A
SCHEMBL27537963 0.68 EGLN1 (0.47) EGLN2EGLN1
SCHEMBL26259639 0.68 EGLN1 (0.52) EGLN1
SCHEMBL18230698 0.67 CA1 (0.42) EGLN2KDM4EEGLN1
SCHEMBL14054114 0.67 CA1 (0.54) KMT2A
SCHEMBL9951399 0.66 FABP4 (0.56) KDM4E
SCHEMBL3187456 0.66 FABP4 (0.56) KDM4E
SCHEMBL27537533 0.66 POLB (0.58) KDM4EKMT2A
SCHEMBL394245 0.66 FABP4 (0.59) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3275881-B1 COMPOUND OF 5-HYDROXYL-1,7-NAPHTHYRIDINE SUBSTITUTED BY ARYLOXY OR HETEROOXY, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE THEREOF SHENYANG SUNSHINE PHARMACEUTICAL CO LTD (CN) 2021-08-04 EP disclosed