Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.54 |
| ▸ | NME4 | O00746 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187456 | 1.00 | FABP4 (0.56) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL6454636 | 0.91 | FABP4 (0.68) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL13286830 | 0.86 | KDM4E (0.65) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL394245 | 0.86 | FABP4 (0.59) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL16784750 | 0.82 | KDM4E (0.61) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL13286803 | 0.82 | KDM4E (0.61) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL3187483 | 0.82 | SIRT5 (0.58) | FABP4TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL24871959 | 0.81 | KDM4E (0.59) | FABP4TDP1KDM4EALDH1A1LMNA | |
| SCHEMBL16144996 | 0.81 | KDM4E (0.59) | TDP1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1669128 | 0.81 | KDM4E (0.59) | TDP1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | FABP4 15/4885TDP1 440/4885KDM4E 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.