Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290976 | 0.87 | PDE3B (0.64) | PDE3BPDE3ATSHRMAPTALDH1A1 | |
| SCHEMBL29158833 | 0.80 | MAPT (0.44) | PDE3BPDE3AMAPTALDH1A1KDM4E | |
| SCHEMBL29159047 | 0.79 | PDE3B (0.42) | PDE3BPDE3AMAPTALDH1A1KDM4E | |
| SCHEMBL4183471 | 0.79 | GCGR (0.78) | PDE3BPDE3AGCGRMAPK1NPSR1 | |
| SCHEMBL30741073 | 0.79 | PDE3B (0.56) | PDE3BPDE3ATSHRMAPTALDH1A1 | |
| SCHEMBL30741015 | 0.78 | GCGR (0.60) | PDE3BPDE3AMAPTALDH1A1KDM4E | |
| SCHEMBL29159037 | 0.78 | GCGR (0.57) | PDE3BPDE3ATSHRMAPTALDH1A1 | |
| SCHEMBL30740993 | 0.78 | GCGR (0.63) | PDE3BPDE3AMAPTALDH1A1KDM4E | |
| SCHEMBL30741049 | 0.78 | PDE3B (0.55) | PDE3BPDE3ATSHRMAPTALDH1A1 | |
| SCHEMBL29158881 | 0.78 | MAPT (0.48) | PDE3BPDE3AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | MGAM, CMBL, MGAM2 | PDE3B 1994/4885PDE3A 1844/4885TSHR 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.