Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732253 | 0.87 | PDE3B (0.63) | PDE3BPDE3ATSHRKDM4EMAPT | |
| SCHEMBL9454856 | 0.82 | ALDH1A1 (0.57) | PDE3BPDE3AKDM4EMAPTALDH1A1 | |
| SCHEMBL30741073 | 0.80 | PDE3B (0.56) | PDE3BPDE3ATSHRKDM4EMAPT | |
| SCHEMBL4183471 | 0.80 | GCGR (0.78) | PDE3BPDE3AGCGRMAPK1 | |
| SCHEMBL30740993 | 0.79 | GCGR (0.63) | PDE3BPDE3AKDM4EMAPTALDH1A1 | |
| SCHEMBL29159037 | 0.79 | GCGR (0.57) | PDE3BPDE3ATSHRKDM4EMAPT | |
| SCHEMBL30741049 | 0.79 | PDE3B (0.55) | PDE3BPDE3ATSHRKDM4EMAPT | |
| SCHEMBL30741015 | 0.79 | GCGR (0.60) | PDE3BPDE3AKDM4EMAPTALDH1A1 | |
| SCHEMBL3493726 | 0.78 | TSHR (0.58) | PDE3BPDE3ATSHRKDM4EMAPT | |
| SCHEMBL30741082 | 0.78 | GCGR (0.58) | PDE3BPDE3AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866484-B | A method of preparing pyrroles, imidazoles, oxazole derivatives | 中国科学院大连化学物理研究所 | 2019-04-09 | — | — | CN | disclosed |