Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 2/20 | 0.42 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371971 | 0.89 | DHODH (0.45) | RORBCTSAMAPTMEN1KMT2A | |
| SCHEMBL2373599 | 0.87 | MAPT (0.41) | RORBCTSAMAPTMEN1KMT2A | |
| SCHEMBL2372846 | 0.84 | CTSA (0.41) | RORBCTSAMAPTMEN1KMT2A | |
| SCHEMBL2373287 | 0.83 | TRPV4 (0.52) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL2372559 | 0.82 | TRPV4 (0.50) | KDM4E | |
| SCHEMBL2372709 | 0.82 | CTSA (0.40) | RORBCTSAMAPTMEN1KMT2A | |
| SCHEMBL2372623 | 0.82 | TRPV4 (0.38) | RORBCTSAMAPTMEN1KMT2A | |
| SCHEMBL2372098 | 0.82 | TRPV4 (0.40) | MAPTMEN1KMT2AKDM4ENAMPT | |
| SCHEMBL2372311 | 0.82 | TRPV4 (0.40) | CTSAMAPTMEN1KMT2AKIFC1 | |
| SCHEMBL2373467 | 0.81 | DHODH (0.52) | RORBCTSAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |