Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | CTSA | P10619 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371971 | 0.90 | DHODH (0.45) | DHODHPDE10ACTSARORBMEN1 | |
| SCHEMBL2373164 | 0.83 | DHODH (0.56) | DHODHPDE10ATSHR | |
| SCHEMBL2372698 | 0.82 | DHODH (0.56) | DHODHPDE10ATSHRRORBMEN1 | |
| SCHEMBL2372552 | 0.82 | DHODH (0.62) | DHODHPDE10ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2372758 | 0.81 | DHODH (0.56) | DHODHPDE10ATSHR | |
| SCHEMBL2373302 | 0.81 | RORB (0.42) | CTSARORBMEN1MAPTKMT2A | |
| SCHEMBL2462422 | 0.81 | DHODH (0.53) | DHODHPDE10ATSHRPIN1 | |
| SCHEMBL2372887 | 0.81 | DHODH (0.53) | DHODHPDE10ATSHRMAPT | |
| SCHEMBL2372855 | 0.80 | DHODH (0.71) | DHODHPDE10ATSHRKMT2A | |
| SCHEMBL2372388 | 0.78 | DHODH (0.53) | DHODHPDE10ATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |