SCHEMBL23733403

SCHEMBL23733403

Ic1cccc(-n2ccc(I)n2)c1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.43
MGLL Q99685 1/20 0.43
MPO P05164 1/20 0.39
KEAP1 Q14145 2/20 0.37
NFE2L2 Q16236 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MPI P34949 1/20 0.35
GRM5 P41594 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 1/20 0.33
NOTUM Q6P988 3/20 0.33
CYP2C9 P11712 1/20 0.32
MAPT P10636 2/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17261505 0.79 CYP2C9 (0.47) MEN1KMT2AALDH1A1NOTUMCYP2C9
SCHEMBL29218271 0.75 KEAP1 (0.50) KEAP1NFE2L2MEN1KMT2APOLB
SCHEMBL3400745 0.73 NOTUM (0.48) FAAHMGLLMPOMEN1KMT2A
SCHEMBL15923683 0.72 CYP2A6 (0.49) HTT
SCHEMBL15824337 0.69 MTOR (0.39) KMT2AALDH1A1CYP2C9MAPTHTT
SCHEMBL15924047 0.69 ELOVL1 (0.40) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL28553990 0.69 MAPT (0.56) FAAHMGLLMPOMEN1KMT2A
SCHEMBL15922629 0.68 KMT2A (0.49) FAAHMGLLMPOKMT2ANOTUM
SCHEMBL15924185 0.68 NOTUM (0.47) KMT2AALDH1A1NOTUMMAPTL3MBTL1
SCHEMBL5168614 0.68 NOTUM (0.60) MEN1KMT2ANOTUMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11566035-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-31 US disclosed
US-20210332072-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-10-28 US disclosed
US-11084838-B2 Organic electroluminescent materials and device UNIVERSAL DISPLAY CORPORATION (US) 2021-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11084838-B2 Organic electroluminescent materials and device OCIAD1, OSBP, OCIAD2 FAAH 555/4885MGLL 126/4885MPO 201/4885
US-20210332072-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OSBP, OCIAD2 FAAH 692/4885MGLL 170/4885MPO 186/4885
US-11566035-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 FAAH 692/4885MGLL 170/4885MPO 186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.