SCHEMBL23733877

SCHEMBL23733877

Fc1ccc(-c2ccc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
RAB9A P51151 5/20 0.46
NPC1 O15118 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
ADORA3 P0DMS8 2/20 0.43
ADORA2A P29274 2/20 0.43
DPP4 P27487 1/20 0.43
TXN P10599 1/20 0.42
ALDH1A1 P00352 1/20 0.41
ALOX5 P09917 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
AHR P35869 1/20 0.41
HRH4 Q9H3N8 1/20 0.41
SIRT2 Q8IXJ6 1/20 0.40
PDGFRB P09619 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17269527 1.00 BCL2L1 (0.48) BCL2L1BADRAB9ANPC1SMN1; SMN2
SCHEMBL6017000 0.97 RAB9A (0.47) BCL2L1BADRAB9ANPC1SMN1; SMN2
SCHEMBL23733798 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733835 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733797 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733818 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733892 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733861 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733794 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1
SCHEMBL23733848 0.90 DPP4 (0.54) BCL2L1BADRAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-24 US disclosed
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-11088331-B2 2021-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 BCL2L1 2154/4885BAD 1638/4885RAB9A 4153/4885
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 BCL2L1 2154/4885BAD 1638/4885RAB9A 4153/4885
US-11088331-B2 DDT, PPOX, DBF4 BCL2L1 2011/4885BAD 2057/4885RAB9A 4158/4885
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME DDT, PPOX, LEF1 BCL2L1 2154/4885BAD 1638/4885RAB9A 4153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.