Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL23734 | 0.99 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL8054070 | 0.99 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL8056551 | 0.99 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL2398487 | 0.99 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL29353083 | 0.99 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL8603228 | 0.99 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL10836210 | 0.97 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL9273939 | 0.97 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL9301984 | 0.97 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL6068328 | 0.95 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393964-B | Graphene modified strong-acid-alkali-resistant electroplating powder coating and preparation method thereof | 常州市碳索新材料科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-111393964-A | Graphene modified strong-acid-alkali-resistant electroplating powder coating and preparation method thereof | 常州市碳索新材料科技有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-111073575-A | Single-component silane modified polyether sealant for prefabricated building and preparation method thereof | 江苏瑞洋安泰新材料科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| WO-2024056473-A1 | MOISTURE-CURABLE COMPOSITION AND ADHESIVE CONTAINING THE COMPOSITION | WACKER CHEMIE AG (DE) | 2024-03-21 | — | — | WO | disclosed |
| EP-4103651-A1 | BITUMINOUS COMPOSITION CONTAINING AN EPOXIDIZED OIL | ARKEMA FRANCE (FR) | 2022-12-21 | — | — | EP | disclosed |
| EP-4103646-A1 | USE OF AN ADDITIVE TO DELAY BITUMEN AGEING | ARKEMA FRANCE (FR) | 2022-12-21 | — | — | EP | disclosed |
| CN-111393964-B | Graphene modified strong-acid-alkali-resistant electroplating powder coating and preparation method thereof | 常州市碳索新材料科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2021160956-A1 | USE OF AN ADDITIVE TO DELAY BITUMEN AGEING | ARKEMA FRANCE (FR) | 2021-08-19 | — | — | WO | disclosed |
| WO-2021160957-A1 | BITUMINOUS COMPOSITION CONTAINING AN EPOXIDIZED OIL | ARKEMA FRANCE (FR) | 2021-08-19 | — | — | WO | disclosed |
| CN-111393964-A | Graphene modified strong-acid-alkali-resistant electroplating powder coating and preparation method thereof | 常州市碳索新材料科技有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-111073575-A | Single-component silane modified polyether sealant for prefabricated building and preparation method thereof | 江苏瑞洋安泰新材料科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| WO-2002092717-A1 | PRESSURE-SENSITIVE ADHESIVE SILICONE COMPOSITIONS, METHOD FOR PREPARING SAME AND USES THEREOF | RHODIA CHIMIE (FR) | 2002-11-21 | — | — | WO | disclosed |
| US-5922781-A | FROM A POLYDIENE DIOL | SHELL OIL COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0667406-B1 | Process for the production of a gamma-radiation resistant polypropylene fibre for a radiation sterilizable non-woven fabric | SUOMINEN OY J W (FI) | 1999-04-21 | — | — | EP | disclosed |
| CN-1189519-A | Method for improving chargeability of powder coating composition | CIBA SC HOLDING AG (CH) | 1998-08-05 | — | — | CN | disclosed |
| US-5747590-A | HARDNESS, WEAR RESISTANCE; AUTOMOBILE FINISHES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0667406-A1 | Process for the production of a gamma-radiation resistant polypropylene fibre for a radiation sterilizable non-woven fabric | J.W. SUOMINEN OY (FI) | 1995-08-16 | — | — | EP | disclosed |
| US-5288777-A | Adding sterically hindered piperidines | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| US-4870121-A | STABILIZED AGAINST ULTRAVIOLET RADIATION | CANADIAN PATENTS & DEVELOPMENT LTD. (CA) | 1989-09-26 | — | — | US | disclosed |
| US-4524165-A | 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE | EASTMAN KODAK COMPANY (US) | 1985-06-18 | — | — | US | disclosed |