SCHEMBL2373426

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31681838	1.00	ROCK1 (0.54)	ROCK1ROCK2PRKACACYP3A4PRKX
	SCHEMBL2373405	0.89	CYP1A2 (0.58)	ROCK1ROCK2CYP3A4CYP2D6CYP2C9
	SCHEMBL29072859	0.85	MMP13 (0.48)	ROCK1ROCK2PRKACAPRKXGSK3A
	SCHEMBL669856	0.85	MMP13 (0.48)	ROCK1ROCK2PRKACAPRKXGSK3A
	SCHEMBL2374833	0.83	MPL (0.52)	CYP3A4CYP2D6MMP13HPGDKMT2A
	SCHEMBL21881739	0.83	SMN1; SMN2 (0.42)	ROCK1ROCK2PRKACACYP3A4PRKX
	SCHEMBL2373894	0.82	HTT (0.55)	ROCK1ROCK2MMP13MAPTKMT2A
	SCHEMBL31681851	0.82	HTT (0.55)	ROCK1ROCK2MMP13MAPTKMT2A
	SCHEMBL2373945	0.82	NAMPT (0.46)	CYP3A4CYP2D6CYP2C9MAPTKMT2A
	SCHEMBL24139180	0.81	SMN1; SMN2 (0.53)	ROCK1ROCK2CYP3A4CYP2C9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.