SCHEMBL2373405

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2373938	0.90	SMN1; SMN2 (0.53)	CYP1A2CYP3A4CYP2C9CYP2C19POLB
	SCHEMBL2373945	0.89	NAMPT (0.46)	CYP1A2CYP3A4CYP2C9CYP2C19POLB
	SCHEMBL24139180	0.89	SMN1; SMN2 (0.53)	CYP1A2CYP3A4CYP2C9CYP2C19POLB
	SCHEMBL31681838	0.89	ROCK1 (0.54)	CYP3A4CYP2C9MAPTCYP2D6ROCK2
	SCHEMBL2373426	0.89	ROCK1 (0.54)	CYP3A4CYP2C9MAPTCYP2D6ROCK2
	SCHEMBL29072859	0.86	MMP13 (0.48)	SMN1; SMN2HTTROCK2ROCK1ALDH1A1
	SCHEMBL669856	0.86	MMP13 (0.48)	SMN1; SMN2HTTROCK2ROCK1ALDH1A1
	SCHEMBL2374577	0.86	MPL (0.46)	SMN1; SMN2ROCK2ROCK1HPGDSMAPK1
	SCHEMBL12254348	0.85	CYP1A2 (0.41)	CYP1A2CYP3A4CYP2C9CYP2C19POLB
	SCHEMBL2373434	0.84	TRPV4 (0.44)	CYP1A2CYP3A4CYP2C9CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.