Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | DDT | P30046 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16501138 | 0.89 | DHFR (0.50) | DHFRHRH4MLYCDATG4BMEN1 | |
| SCHEMBL669856 | 0.85 | MMP13 (0.48) | MPLMAPK1GAAMMP13LMNA | |
| SCHEMBL29072859 | 0.85 | MMP13 (0.48) | MPLMAPK1GAAMMP13LMNA | |
| SCHEMBL2373426 | 0.83 | ROCK1 (0.54) | CYP3A4CYP2D6KMT2AMMP13HPGD | |
| SCHEMBL31681838 | 0.83 | ROCK1 (0.54) | CYP3A4CYP2D6KMT2AMMP13HPGD | |
| SCHEMBL31681851 | 0.82 | HTT (0.55) | MEN1KMT2AMMP13LMNAALDH1A1 | |
| SCHEMBL2373894 | 0.82 | HTT (0.55) | MEN1KMT2AMMP13LMNAALDH1A1 | |
| SCHEMBL27913945 | 0.81 | MEN1 (0.59) | DHFRHRH4MLYCDATG4BMEN1 | |
| SCHEMBL24139180 | 0.79 | SMN1; SMN2 (0.53) | MPLMAPK1MEN1CYP1A2CYP3A4 | |
| SCHEMBL2374577 | 0.79 | MPL (0.46) | MPLMAPK1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410397-B2 | Methods of enhancing cell survival of stem cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-09-09 | — | — | US | disclosed |
| EP-4585589-A2 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-4296270-B1 | A COMPOSITION COMPRISING STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2025-06-18 | — | — | EP | disclosed |
| EP-4296270-A2 | A COMPOSITION COMPRISING STEM CELL CULTURES | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3936508-B1 | A COMPOSITION COMPRISING STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3936508-A1 | A COMPOSITION COMPRISING STEM CELL CULTURES | The Scripps Research Institute (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20210403862-A1 | METHODS OF ENHANCING CELL SURVIVAL OF STEM CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2021-12-30 | — | — | US | disclosed |
| US-20210403862-A1 | METHODS OF ENHANCING CELL SURVIVAL OF STEM CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2021-12-30 | — | — | US | disclosed |
| EP-3623374-B1 | STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3623374-B1 | STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-2370445-B1 | STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2014-07-23 | — | — | EP | disclosed |
| EP-2370445-B1 | STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2014-07-23 | — | — | EP | disclosed |
| US-20110294761-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-12-01 | — | — | US | disclosed |
| US-8044201-B2 | Stem cell cultures | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044201-B2 | Stem cell cultures | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044201-B2 | Stem cell cultures | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110224233-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224233-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224233-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010065721-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294761-A1 | STEM CELL CULTURES | NES, CD44, MCL1 | MPL 819/4885DHFR 2743/4885MAPK1 3418/4885 |
| US-12410397-B2 | Methods of enhancing cell survival of stem cells | MCL1, BCL2, BCLAF1 | MPL 1128/4885DHFR 1545/4885MAPK1 3981/4885 |
| US-20210403862-A1 | METHODS OF ENHANCING CELL SURVIVAL OF STEM CELLS | MCL1, BCL2, BCLAF1 | MPL 1128/4885DHFR 1545/4885MAPK1 3981/4885 |
| US-20110224233-A1 | STEM CELL CULTURES | NES, CD44, MCL1 | MPL 819/4885DHFR 2743/4885MAPK1 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.