SCHEMBL2373945

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2373405	0.89	CYP1A2 (0.58)	CYP2C9CYP1A2CYP3A4CYP2C19POLB
	SCHEMBL2374577	0.89	MPL (0.46)	TRPV4MPLSMN1; SMN2
	SCHEMBL24139180	0.88	SMN1; SMN2 (0.53)	TRPV4CYP2C9CYP1A2CYP3A4CYP2C19
	SCHEMBL2373434	0.87	TRPV4 (0.44)	TRPV4CYP2C9CYP1A2CYP3A4CYP2C19
	SCHEMBL29072859	0.86	MMP13 (0.48)	NAMPTMPLSMN1; SMN2HTT
	SCHEMBL669856	0.86	MMP13 (0.48)	NAMPTMPLSMN1; SMN2HTT
	SCHEMBL2374491	0.85	NAMPT (0.48)	NAMPTTRPV4MPLSMN1; SMN2HTT
	SCHEMBL12254348	0.84	CYP1A2 (0.41)	TRPV4CYP2C9CYP1A2CYP3A4CYP2C19
	SCHEMBL31681838	0.82	ROCK1 (0.54)	CYP2C9CYP3A4KMT2AMAPTCYP2D6
	SCHEMBL2373426	0.82	ROCK1 (0.54)	CYP2C9CYP3A4KMT2AMAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.