Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025216 | 0.82 | MAPK1 (0.46) | MAPK1PPARGPPARADRD2DRD4 | |
| SCHEMBL23735024 | 0.82 | KDM4E (0.44) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL19989562 | 0.82 | MAPK1 (0.42) | MAPK1PPARGPPARADRD2DRD4 | |
| SCHEMBL23735090 | 0.80 | QDPR (0.39) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL20025573 | 0.79 | MAPK1 (0.47) | MAPK1PPARGPPARADRD2DRD4 | |
| SCHEMBL23735038 | 0.78 | PPARG (0.43) | PPARGPPARAKDM4ESIGMAR1S1PR1 | |
| SCHEMBL23735012 | 0.78 | DRD2 (0.40) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL20025535 | 0.78 | MAPK1 (0.41) | MAPK1PPARGPPARADRD2DRD4 | |
| SCHEMBL23735066 | 0.77 | PPARG (0.37) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL23734914 | 0.77 | DRD2 (0.40) | PPARGPPARADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519387-B1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG A ST CO LTD (KR) | 2021-08-11 | — | — | EP | disclosed |