SCHEMBL23736372

SCHEMBL23736372

CCCCCC(O)N(C(C)CC)C(O)CCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 2/20 0.47
TP53 P04637 2/20 0.41
OPRM1 P35372 1/20 0.39
GPR84 Q9NQS5 5/20 0.38
CA1 P00915 2/20 0.38
FFAR1 O14842 1/20 0.38
LMNA P02545 2/20 0.37
CYP2D6 P10635 2/20 0.35
GMNN O75496 1/20 0.35
POLB P06746 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
BLM P54132 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
CETP P11597 1/20 0.35
HTT P42858 1/20 0.35
UBE2N P61088 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23736358 0.93 SPHK1 (0.39) SPHK1TP53CA1CYP3A4
SCHEMBL23736364 0.84 TSHR (0.36) SPHK1LMNA
SCHEMBL465349 0.84 GPR84 (0.44) SPHK1TP53OPRM1GPR84FFAR1
SCHEMBL23736361 0.82 TP53 (0.48) SPHK1TP53OPRM1GPR84CA1
SCHEMBL14446359 0.81 GPR84 (0.48) SPHK1TP53GPR84FFAR1LMNA
SCHEMBL37135 0.81 GPR84 (0.48) SPHK1TP53GPR84FFAR1LMNA
SCHEMBL9700521 0.81 GPR84 (0.48) SPHK1TP53GPR84FFAR1LMNA
SCHEMBL11449796 0.81 SPHK1 (0.45) SPHK1TP53GPR84FFAR1LMNA
SCHEMBL23736388 0.76 TSHR (0.42)
SCHEMBL920167 0.76 ALDH1A1 (0.40) SPHK1TP53GPR84CA1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230104687-A1 NOVEL AMINE COMPOUND, ACID GAS ABSORBENT, METHOD FOR REMOVING ACID GAS, AND ACID GAS REMOVAL APPARATUS KABUSHIKI KAISHA TOSHIBA (JP) 2023-04-06 US disclosed
CN-115805003-A Novel amine compound, acid gas absorbent, method for removing acid gas, and acid gas removal device 株式会社东芝 2023-03-17 CN disclosed
US-11090603-B2 Acidic gas absorbent, acidic gas removal method and acidic gas removal apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2021-08-17 US disclosed