Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541545 | 0.93 | NOS3 (0.48) | NOS3NOS1NOS2CHRM3CHRM2 | |
| SCHEMBL31309223 | 0.85 | LTA4H (0.47) | SMN1; SMN2NOS3NOS1NOS2LTA4H | |
| SCHEMBL9117247 | 0.82 | PDE4A (0.49) | SMN1; SMN2NOS3NOS1NOS2LTA4H | |
| SCHEMBL14634346 | 0.78 | CHRNB2 (0.47) | SMN1; SMN2KDM4ENPY1RNPY2RLRRK2 | |
| SCHEMBL2557423 | 0.78 | CHRNB2 (0.47) | SMN1; SMN2KDM4ENPY1RNPY2RLRRK2 | |
| SCHEMBL4515007 | 0.78 | HRH1 (0.51) | HRH1LTA4HMAPK14 | |
| SCHEMBL30292528 | 0.77 | KDM4E (0.55) | SMN1; SMN2KDM4ENPY1RNPY2RHRH1 | |
| SCHEMBL30978673 | 0.76 | SCD (0.46) | SMN1; SMN2KDM4ENPY1RNPY2RHRH1 | |
| SCHEMBL31234741 | 0.76 | NAMPT (0.44) | RBP4KMT2A | |
| SCHEMBL12929421 | 0.75 | LRRK2 (0.48) | SMN1; SMN2LRRK2HRH3CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727756-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113956238-B | Protein kinase inhibitor and preparation method and medical application thereof | 甘李药业股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-108290864-B | Protein kinase inhibitor and preparation method and medical application thereof | 甘李药业股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-113956238-A | Protein kinase inhibitor and preparation method and medical application thereof | 甘李药业股份有限公司 | 2022-01-21 | — | — | CN | disclosed |
| US-11091476-B2 | Protein kinase inhibitors, preparation method and medical use thereof | GAN & LEE PHARMACEUTICALS | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091476-B2 | Protein kinase inhibitors, preparation method and medical use thereof | ROR1, DMPK, CDK9 | SMN1; SMN2 811/4885KDM4E 1343/4885NPY1R 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.