Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770601 | 0.90 | MEN1 (0.43) | THRBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26597164 | 0.88 | THRB (0.37) | THRBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23718668 | 0.87 | TSHR (0.41) | THRBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7066945 | 0.83 | MEN1 (0.41) | THRBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26597356 | 0.81 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL11996079 | 0.80 | ALDH1A1 (0.40) | THRBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23718675 | 0.79 | MEN1 (0.36) | THRBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23718629 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL23718618 | 0.77 | L3MBTL1 (0.39) | MEN1KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL23718625 | 0.77 | MEN1 (0.34) | MEN1KMT2AALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861976-A1 | DENTAL MATERIALS BASED ON CYCLOPOLYMERISABLE CROSS-LINKING AGENTS | Ivoclar Vivadent AG (LI) | 2021-08-11 | — | — | EP | disclosed |