SCHEMBL11996079

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2770601	0.89	MEN1 (0.43)	ALDH1A1TSHRGAAMGAMSI
	SCHEMBL12677204	0.87	CYP2D6 (0.35)	ALDH1A1TSHRGAAPTPN1PTPRB
	SCHEMBL7066945	0.85	MEN1 (0.41)	ALDH1A1TSHREGLN1MAPTCYP2C19
	SCHEMBL6049017	0.82	ALDH1A1 (0.38)	ALDH1A1TSHREGLN1MAPTCYP2D6
	SCHEMBL7919109	0.82	PTPN1 (0.48)	ALDH1A1GAAPTPN1PTPRBACP1
	SCHEMBL23280506	0.81	ALDH1A1 (0.30)	ALDH1A1TSHR
	SCHEMBL23736641	0.80	THRB (0.42)	ALDH1A1TSHRMAPTCYP2C19PKM
	SCHEMBL26597356	0.80	MEN1 (0.37)	ALDH1A1TSHRMAPTPKMMEN1
	SCHEMBL23718668	0.80	TSHR (0.41)	ALDH1A1TSHRMAPTPKMMEN1
	SCHEMBL23718675	0.78	MEN1 (0.36)	ALDH1A1TSHRMAPTCYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.