SCHEMBL23737855

SCHEMBL23737855

c1ccc2c(-c3ccc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6cccc7c6sc6ccccc67)ccc54)cc3)cccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
PRKDC P78527 3/20 0.35
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F9 P00740 1/20 0.32
ALK Q9UM73 1/20 0.32
POLB P06746 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
TUBA1B P68363 1/20 0.30
TUBA4A P68366 1/20 0.30
TUBB4B P68371 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24765552 0.93 ALOX5 (0.35) ALOX5PRKDCCA12CA1CA2
SCHEMBL10165703 0.92 ALOX5 (0.49) ALOX5PRKDCCA12CA1CA2
SCHEMBL17248395 0.92 ALOX5 (0.48) ALOX5PRKDCCA12CA1CA2
SCHEMBL23737865 0.91 ALOX5 (0.43) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16171582 0.91 ALOX5 (0.42) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL19933634 0.89 ALOX5 (0.51) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL780770 0.88 ALOX5 (0.46) ALOX5PRKDCCA12CA1CA2
SCHEMBL23468824 0.88 ALOX5 (0.37) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL18505069 0.88 ALOX5 (0.46) ALOX5PRKDCCA12CA1CA2
SCHEMBL22078468 0.88 ALOX5 (0.45) ALOX5PRKDCKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-02-16 US disclosed
EP-3863077-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
EP-3863077-A1 ORGANIC LIGHT EMITTING DIODE LG Chem, Ltd. (KR) 2021-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, ELOVL1, CRY1 ALOX5 642/4885PRKDC 3901/4885CA12 2006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.