Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23740007 | 0.91 | MAPT (0.34) | HTR1ASLC6A4 | |
| SCHEMBL23739830 | 0.85 | IDO1 (0.36) | — | |
| SCHEMBL23739943 | 0.83 | HTR1A (0.31) | HTR1ASLC6A4 | |
| SCHEMBL23739523 | 0.83 | IDO1 (0.36) | — | |
| SCHEMBL23739619 | 0.82 | IDO1 (0.36) | — | |
| SCHEMBL23739919 | 0.82 | IDO1 (0.36) | — | |
| SCHEMBL23739743 | 0.77 | HTR2A (0.33) | — | |
| SCHEMBL23739922 | 0.77 | ACKR3 (0.37) | — | |
| SCHEMBL23739656 | 0.76 | IDO1 (0.38) | — | |
| SCHEMBL23739734 | 0.75 | NR1H2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862348-A1 | ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |