Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739272 | 0.79 | ALDH1A1 (0.54) | ALDH1A1RAB9AL3MBTL1LMNACASP1 | |
| SCHEMBL10932638 | 0.78 | ALDH1A1 (0.67) | ALDH1A1RAB9AL3MBTL1LMNAHTT | |
| SCHEMBL2489789 | 0.78 | ALDH1A1 (0.42) | ALDH1A1RAB9AL3MBTL1LMNAHTT | |
| SCHEMBL15687877 | 0.78 | CASP1 (0.58) | ALDH1A1RAB9AL3MBTL1LMNACASP1 | |
| SCHEMBL2260994 | 0.76 | ALDH1A1 (0.57) | ALDH1A1RAB9AL3MBTL1LMNACASP1 | |
| SCHEMBL5739260 | 0.74 | RORC (0.57) | ALDH1A1RAB9AL3MBTL1LMNACASP1 | |
| SCHEMBL5740765 | 0.74 | ALDH1A1 (0.63) | ALDH1A1RAB9AL3MBTL1LMNACASP1 | |
| SCHEMBL18383188 | 0.74 | ALDH1A1 (0.43) | ALDH1A1RAB9AL3MBTL1LMNAHTT | |
| SCHEMBL104396 | 0.72 | KEAP1 (0.48) | ALDH1A1RAB9AL3MBTL1LMNACASP1 | |
| SCHEMBL29412881 | 0.72 | KEAP1 (0.48) | ALDH1A1RAB9AL3MBTL1LMNACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550264-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| US-9040537-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| EP-2550264-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2013-01-30 | — | — | EP | disclosed |
| US-20130012380-A1 | Pyridazine Compounds For Controlling Invertebrate Pests | BASF SE (DE) | 2013-01-10 | — | — | US | disclosed |
| WO-2011117286-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012380-A1 | Pyridazine Compounds For Controlling Invertebrate Pests | GRIN2C, GRIN2A, NR2C2 | ALDH1A1 1363/4885RAB9A 1336/4885L3MBTL1 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.