Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 6/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373510 | 0.80 | PPID (0.50) | PPIDCDC7DBF4HDAC1GPR142 | |
| SCHEMBL2375909 | 0.71 | GPR142 (0.47) | PPIDHDAC1GPR142CYP26A1ROCK2 | |
| SCHEMBL2374561 | 0.70 | PPID (0.48) | PPIDHDAC1GPR142PDCD1CD274 | |
| SCHEMBL2374570 | 0.70 | PPID (0.48) | PPIDHDAC1GPR142PDCD1CD274 | |
| SCHEMBL2376148 | 0.70 | PPID (0.41) | PPIDHDAC1GPR142POLBKMT2A | |
| SCHEMBL1124572 | 0.69 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL21879064 | 0.68 | ALDH1A1 (0.39) | ALDH1A1POLBPKMKMT2AMEN1 | |
| SCHEMBL1931193 | 0.67 | MMP8 (0.56) | PPIDPOLB | |
| SCHEMBL29788300 | 0.67 | MAPT (0.49) | PPIDALDH1A1POLBMAPTKMT2A | |
| SCHEMBL13915549 | 0.67 | MMP8 (0.56) | PPIDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | CTSA, BECN1, HDAC6 | PPID 654/4885CDC7 3765/4885DBF4 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.