Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515404 | 1.00 | HTT (0.53) | HTTCYP1A2CYP2C19CYP3A4LMNA | |
| SCHEMBL13286604 | 0.83 | DHFR (0.53) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL30022928 | 0.83 | DHFR (0.53) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL12553474 | 0.82 | NPC1 (0.50) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL30185055 | 0.81 | L3MBTL1 (0.54) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL30185058 | 0.81 | L3MBTL1 (0.54) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL166826 | 0.81 | L3MBTL1 (0.54) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL29390114 | 0.81 | L3MBTL1 (0.54) | HTTCYP3A4LMNACCR1CCR8 | |
| SCHEMBL912017 | 0.80 | CCR1 (0.53) | HTTCYP3A4LMNANQO2CCR1 | |
| SCHEMBL31036114 | 0.80 | CCR1 (0.53) | HTTCYP3A4LMNANQO2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420990-B2 | Ruthenium complex containing alkynyl group, method of synthesizing the same and use thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY (CN) | 2022-08-23 | — | — | US | disclosed |
| US-20210246154-A1 | RUTHENIUM COMPLEX CONTAINING ALKYNYL GROUP, METHOD OF SYNTHESIZING THE SAME AND USE THEREOF | GUANGDONG PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246154-A1 | RUTHENIUM COMPLEX CONTAINING ALKYNYL GROUP, METHOD OF SYNTHESIZING THE SAME AND USE THEREOF | HRH1, SLC7A5, SLC43A1 | HTT 4783/4885CYP1A2 1488/4885CYP2C19 1925/4885 |
| US-11420990-B2 | Ruthenium complex containing alkynyl group, method of synthesizing the same and use thereof | HRH1, SLC7A5, SLC43A1 | HTT 4783/4885CYP1A2 1488/4885CYP2C19 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.