Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997992 | 0.78 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL9944368 | 0.77 | ALOX15 (0.71) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL707094 | 0.77 | CA12 (0.67) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL9944364 | 0.76 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL8041186 | 0.75 | CA12 (0.65) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL9944374 | 0.75 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL9944380 | 0.75 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL43683 | 0.75 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL701832 | 0.74 | CA12 (0.83) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL9944375 | 0.73 | MEN1 (0.58) | NPC1RAB9AMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034857-B2 | Methods for reducing superoxide anions in eukaryotic organisms | HEALTH RESEARCH, INC. (US) | 2015-05-19 | — | — | US | disclosed |
| US-20130150336-A1 | Methods For Reducing Superoxide Anions in Eukaryotic Organisms | STC.UNM (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011119798-A1 | METHODS FOR REDUCING SUPEROXIDE ANIONS IN EUKARYOTIC ORGANISMS | HEALTH RESEARCH, INC. (US) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150336-A1 | Methods For Reducing Superoxide Anions in Eukaryotic Organisms | TXN2, TXNRD2, PRDX5 | NPC1 1704/4885RAB9A 3105/4885MEN1 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.