Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.73 |
| ▸ | BCR | P11274 | 6/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.73 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.73 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.73 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.73 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.73 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.73 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.73 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.73 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.73 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.73 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027189 | 0.90 | HDAC4 (0.62) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL23743214 | 0.85 | CYP1A1 (1.00) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL28640151 | 0.84 | ABL1 (0.62) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL1026075 | 0.84 | HSD17B1 (0.68) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL6068053 | 0.84 | ABL1 (0.62) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL5620245 | 0.83 | CYP3A4 (0.86) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL29431754 | 0.80 | CYP11B1 (0.57) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL2545199 | 0.80 | ABCB1 (0.62) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL2090901 | 0.79 | ABL1 (0.57) | ABL1BCRABCB1CYP3A4CYP2C9 | |
| SCHEMBL12110244 | 0.79 | CYP11B1 (0.59) | ABL1BCRABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2019165159-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | ABL1 3986/4885BCR 4193/4885ABCB1 2152/4885 |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, LOX | ABL1 3986/4885BCR 4193/4885ABCB1 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.