Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | IL17A | Q16552 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24182496 | 0.79 | MAOA (0.34) | SMN1; SMN2NOTUMTSHR | |
| SCHEMBL23745290 | 0.75 | ADAMTS5 (0.45) | — | |
| SCHEMBL23745293 | 0.72 | ADAMTS5 (0.48) | — | |
| SCHEMBL24182481 | 0.72 | ADAMTS4 (0.46) | — | |
| SCHEMBL24182484 | 0.72 | ADAMTS4 (0.46) | — | |
| SCHEMBL23727429 | 0.72 | ADAMTS5 (0.48) | — | |
| SCHEMBL23745388 | 0.72 | ADAMTS5 (0.48) | — | |
| SCHEMBL24182486 | 0.72 | ADAMTS4 (0.46) | — | |
| SCHEMBL418202 | 0.65 | DRD4 (0.51) | SMN1; SMN2NOTUMKMT2A | |
| SCHEMBL23728136 | 0.65 | PNMT (0.36) | SMN1; SMN2NOTUMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |