SCHEMBL2374536

SCHEMBL2374536

Fc1c2ccc-2c1F.OBO

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592635 0.80 ALDH1A1 (0.35)
Boric Acid SCHEMBL3714295 0.79 ORAI1 (0.36) ESR1ESR2
SCHEMBL27562234 0.76
Thiourea SCHEMBL6835360 0.73 TSHR (0.38)
SCHEMBL4451075 0.73 AR (0.46) ESR1ESR2
SCHEMBL5716618 0.71 CTSL (0.44) ESR1ESR2
SCHEMBL4958933 0.69 ORAI1 (0.47)
SCHEMBL8020031 0.69 CTSS (0.38)
SCHEMBL5892467 0.67 ESR1 (0.52) ESR1ESR2
SCHEMBL18069659 0.67 POLB (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513051-B Compound and color conversion film comprising the same 株式会社LG化学 2023-12-26 CN disclosed
EP-4279565-A2 THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2023-11-22 EP disclosed
CN-109554181-B Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2023-10-31 CN disclosed
EP-3763802-B1 THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-09-06 EP disclosed
CN-109207161-B Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2023-08-22 CN disclosed
CN-110023457-B Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2023-08-18 CN disclosed
EP-4126878-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2023-02-08 EP disclosed
CN-111148734-B Pyrrole-2-formamide compound and preparation method and application thereof 中国医学科学院药物研究所 2023-01-06 CN disclosed
US-11168255-B2 Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-11-09 US disclosed
US-11060029-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-07-13 US disclosed
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2006-08-10 US disclosed
CN-1474826-A Light emitting device and display ������������ʽ���� 2004-02-11 CN disclosed
EP-1348711-A1 LUMINESCENT ELEMENT AND DISPLAY CANON KABUSHIKI KAISHA (JP) 2003-10-01 EP disclosed
US-20030068526-A1 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed
EP-1246797-A1 CYCLOPENTYL SULFONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2002-10-09 EP disclosed
EP-1189905-A1 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES Bristol-Myers Squibb Pharma Company (US) 2002-03-27 EP disclosed
WO-2001042203-A1 CYCLOPENTYL SULFONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2001-06-14 WO disclosed
WO-2000077001-A1 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES DU PONT PHARMACEUTICALS COMPANY (US) 2000-12-21 WO disclosed
EP-0968158-A1 METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM Basell Polyolefine GmbH (DE) 2000-01-05 EP disclosed
WO-1998040331-A1 PREPARATION OF PREPARING SUBSTITUTED INDANONES TARGOR GMBH (DE) 1998-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency AP3M1, MLEC, MLX ESR1 3111/4885ESR2 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.