Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 15/20 | 0.66 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.55 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745420 | 0.86 | ADAMTS5 (0.56) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL23745344 | 0.84 | ADAMTS5 (0.55) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL23745408 | 0.84 | ADAMTS5 (0.58) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL30013015 | 0.82 | ADAMTS5 (0.64) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL23745222 | 0.82 | ADAMTS5 (0.53) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL23745212 | 0.81 | ADAMTS5 (0.52) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL23745332 | 0.79 | ADAMTS5 (0.52) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL19701803 | 0.79 | ADAMTS5 (0.69) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL19691588 | 0.79 | ADAMTS5 (0.69) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL19691415 | 0.77 | ADAMTS5 (0.64) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |