Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 4/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23722030 | 0.99 | KRAS (0.37) | KRASSOS1CCR3OPRM1OPRK1 | |
| SCHEMBL23745729 | 0.89 | KDM4E (0.35) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL23745689 | 0.88 | KDM4E (0.40) | OPRM1OPRK1OPRL1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL23721978 | 0.88 | KDM4E (0.35) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL23721853 | 0.88 | SLC7A5 (0.34) | KDM4E | |
| Hydrochloric Acid SCHEMBL23722027 | 0.87 | KDM4E (0.39) | OPRM1OPRK1OPRL1KDM4EMEN1 | |
| SCHEMBL23722133 | 0.87 | OPRM1 (0.35) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL23745720 | 0.87 | KDM4E (0.35) | CCR3OPRM1OPRK1OPRL1OPRD1 | |
| Hydrochloric Acid SCHEMBL23722052 | 0.86 | OPRM1 (0.36) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL23722158 | 0.86 | KDM4E (0.35) | CCR3OPRM1OPRK1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | FDPS, FPR1, F12 | KRAS 2258/4885SOS1 2902/4885CCR3 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.