Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23721978 | 0.99 | KDM4E (0.35) | KDM4EALDH1A1POLBNPSR1MEN1 | |
| SCHEMBL23745689 | 0.91 | KDM4E (0.40) | KDM4EMEN1KMT2AHTR6OPRM1 | |
| Hydrochloric Acid SCHEMBL23722027 | 0.90 | KDM4E (0.39) | KDM4EMEN1KMT2AHTR6OPRM1 | |
| SCHEMBL23722133 | 0.89 | OPRM1 (0.35) | KDM4EALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL23745720 | 0.89 | KDM4E (0.35) | KDM4EMEN1KMT2AHTR6OPRM1 | |
| SCHEMBL23745486 | 0.89 | KRAS (0.38) | KDM4EALDH1A1MEN1KMT2AOPRM1 | |
| Hydrochloric Acid SCHEMBL23722158 | 0.89 | KDM4E (0.35) | KDM4EMEN1KMT2AHTR6OPRM1 | |
| Hydrochloric Acid SCHEMBL23722052 | 0.89 | OPRM1 (0.36) | KDM4EALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL23745765 | 0.88 | OPRM1 (0.36) | KDM4EALDH1A1MEN1KMT2AHTR6 | |
| Hydrochloric Acid SCHEMBL23721923 | 0.88 | OPRM1 (0.37) | KDM4EALDH1A1MEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | FDPS, FPR1, F12 | KDM4E 4474/4885ALDH1A1 1197/4885POLB 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.