SCHEMBL23745640

SCHEMBL23745640

Cc1cccc(C(CC(=O)N[C@H]2CC[C@H](N)CC2)c2cn(Cc3ccccc3)c3ccccc23)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMYD3 Q9H7B4 1/20 0.42
ICMT O60725 1/20 0.42
TP53 P04637 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPT P10636 2/20 0.39
DCUN1D1 Q96GG9 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
BRD4 O60885 1/20 0.39
KDM1A O60341 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23745803 1.00 CNR1 (0.44) CNR1CNR2USP2ALDH1A1POLB
SCHEMBL23721915 1.00 CNR1 (0.44) CNR1CNR2USP2ALDH1A1POLB
Hydrochloric Acid SCHEMBL23721944 0.99 CNR1 (0.44) CNR1CNR2USP2ALDH1A1POLB
SCHEMBL23745546 0.90 ICMT (0.43) CNR1ALDH1A1POLBICMTTP53
SCHEMBL23745786 0.90 CNR1 (0.44) CNR1CNR2USP2ALDH1A1POLB
SCHEMBL23745444 0.89 SIGMAR1 (0.47) CNR1CNR2USP2ALDH1A1POLB
Hydrochloric Acid SCHEMBL23722180 0.89 ICMT (0.43) CNR1ALDH1A1POLBICMTTP53
Hydrochloric Acid SCHEMBL23721982 0.89 CNR1 (0.44) CNR1CNR2USP2ALDH1A1POLB
Hydrochloric Acid SCHEMBL23722170 0.89 SIGMAR1 (0.47) CNR1CNR2USP2ALDH1A1POLB
SCHEMBL23745719 0.88 CNR1 (0.41) CNR1USP2ALDH1A1ICMTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF BIOIMICS AB (SE) 2021-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF FDPS, FPR1, F12 CNR1 1651/4885CNR2 2528/4885USP2 4595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.