SCHEMBL2374577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL669856	0.90	MMP13 (0.48)	MPLSMN1; SMN2ROCK2RPS6KA5MAP4K4
	SCHEMBL29072859	0.90	MMP13 (0.48)	MPLSMN1; SMN2ROCK2RPS6KA5MAP4K4
	SCHEMBL2373945	0.89	NAMPT (0.46)	MPLTRPV4SMN1; SMN2
	SCHEMBL24139180	0.88	SMN1; SMN2 (0.53)	MPLTRPV4SMN1; SMN2ROCK2MAPK1
	SCHEMBL2373434	0.88	TRPV4 (0.44)	MPLTRPV4SMN1; SMN2MAPK1
	SCHEMBL12254348	0.87	CYP1A2 (0.41)	MPLTRPV4SMN1; SMN2ROCK2MAPK1
	SCHEMBL2373405	0.86	CYP1A2 (0.58)	SMN1; SMN2HPGDSROCK2MAPK1ROCK1
	SCHEMBL2374491	0.86	NAMPT (0.48)	MPLTRPV4SMN1; SMN2
	SCHEMBL2373894	0.83	HTT (0.55)	SMN1; SMN2ROCK2ROCK1MMP13
	SCHEMBL31681851	0.83	HTT (0.55)	SMN1; SMN2ROCK2ROCK1MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.