Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23746019 | 0.87 | CA1 (0.36) | CA1CA2P4HBALOX5CA12 | |
| SCHEMBL23745930 | 0.86 | CA1 (0.39) | CA1CA2P4HBALOX5CA12 | |
| SCHEMBL23745977 | 0.81 | CA1 (0.34) | CA1CA2P4HBNQO2CYP3A4 | |
| SCHEMBL21693455 | 0.79 | HSD11B1 (0.46) | CA1CA2MMP13CA12CA9 | |
| SCHEMBL28549912 | 0.79 | HSD11B1 (0.46) | CA1CA2MMP13CA12CA9 | |
| SCHEMBL23745906 | 0.78 | STAT3 (0.39) | CA1CA2CA12CA9CYP2C19 | |
| SCHEMBL23746004 | 0.75 | CA1 (0.48) | CA1CA2CA12CA9CYP3A4 | |
| SCHEMBL30633644 | 0.74 | CD74 (0.35) | — | |
| SCHEMBL23723339 | 0.74 | STAT3 (0.46) | CA1CA2 | |
| SCHEMBL23723336 | 0.74 | STAT3 (0.46) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155439-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2021-08-12 | — | — | WO | disclosed |