Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 5/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745931 | 0.86 | MAOB (0.36) | CA1CA2MTNR1AMTNR1B | |
| SCHEMBL30633632 | 0.86 | KCNQ4 (0.35) | MAPK1P4HBMTNR1AMTNR1B | |
| SCHEMBL23745978 | 0.81 | CA1 (0.43) | CA1CA2CYP3A4CYP2C19P4HB | |
| SCHEMBL23745932 | 0.80 | NQO2 (0.41) | MAPK1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30633625 | 0.79 | CTSK (0.35) | CA1CA2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL23746020 | 0.79 | CTSK (0.35) | CA1CA2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL26758437 | 0.78 | IDO1 (0.41) | CA1LMNAALDH1A1TSHRMALT1 | |
| SCHEMBL23723262 | 0.78 | APEX1 (0.48) | LMNAHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL23745972 | 0.78 | ALDH1A1 (0.36) | LMNAALDH1A1TSHRIDO1NQO2 | |
| SCHEMBL23723265 | 0.78 | APEX1 (0.48) | LMNAHPGDALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155439-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2021-08-12 | — | — | WO | disclosed |