SCHEMBL23746004

SCHEMBL23746004

C#CCNC(=O)c1ccc(S(=O)(=O)C/C(F)=C/CNC(=O)OC(C)(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.48
CA2 P00918 10/20 0.48
CA12 O43570 6/20 0.48
CA9 Q16790 6/20 0.48
CA14 Q9ULX7 1/20 0.48
EGFR P00533 1/20 0.41
LMNA P02545 1/20 0.36
ALDH1A1 P00352 2/20 0.34
EPHX2 P34913 2/20 0.34
NR1H4 Q96RI1 2/20 0.34
NPC1 O15118 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NAMPT P43490 1/20 0.34
CD274 Q9NZQ7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23723387 0.85 CA2 (0.54) CA1CA2CA12CA9CA14
SCHEMBL23723390 0.85 CA2 (0.54) CA1CA2CA12CA9CA14
SCHEMBL21693479 0.83 CA1 (0.40) CA1CA2CA12CA9EPHX2
SCHEMBL28549912 0.82 HSD11B1 (0.46) CA1CA2CA12CA9CA14
SCHEMBL21693455 0.82 HSD11B1 (0.46) CA1CA2CA12CA9CA14
SCHEMBL23746003 0.81 CA12 (0.39) CA1CA2CA12CA9CA14
SCHEMBL23746019 0.76 CA1 (0.36) CA1CA2CA12CA9NPC1
SCHEMBL23745906 0.76 STAT3 (0.39) CA1CA2CA12CA9LMNA
SCHEMBL23745978 0.75 CA1 (0.43) CA1CA2CA12CA9CYP3A4
SCHEMBL23745930 0.75 CA1 (0.39) CA1CA2CA12CA9EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO CA1 1688/4885CA2 1164/4885CA12 1829/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 CA1 3371/4885CA2 2607/4885CA12 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.