SCHEMBL23723339

SCHEMBL23723339

CC(C)(C)OC(=O)NCC=C(F)CS(=O)(=O)c1cccc(C(=O)Nc2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
PKM P14618 1/20 0.44
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGB1 P05556 1/20 0.38
ITGAV P06756 1/20 0.38
ITGA2B P08514 1/20 0.38
ITGB5 P18084 1/20 0.38
KAT6A Q92794 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23723336 1.00 STAT3 (0.46) STAT3L3MBTL1PKMMEN1KMT2A
SCHEMBL23745906 0.90 STAT3 (0.39) STAT3L3MBTL1MEN1KMT2ALMNA
SCHEMBL23723229 0.81 L3MBTL1 (0.45) STAT3L3MBTL1PKMMEN1KMT2A
SCHEMBL23723228 0.81 L3MBTL1 (0.45) STAT3L3MBTL1PKMMEN1KMT2A
SCHEMBL28549912 0.81 HSD11B1 (0.46) KMT2ANPC1RAB9ACA1CA2
SCHEMBL21693455 0.81 HSD11B1 (0.46) KMT2ANPC1RAB9ACA1CA2
SCHEMBL30633629 0.74 MEN1 (0.47) STAT3L3MBTL1PKMMEN1KMT2A
SCHEMBL23745978 0.74 CA1 (0.43) CA1CA2
SCHEMBL21693479 0.74 CA1 (0.40) CA1CA2
SCHEMBL30782049 0.73 MEP1B (0.40) STAT3L3MBTL1LMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO STAT3 4794/4885L3MBTL1 589/4885PKM 2307/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 STAT3 4085/4885L3MBTL1 142/4885PKM 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.